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Defibrotide enhances fibrinolysis in human endotoxemia – a randomized, double blind, crossover trial in healthy volunteers
Defibrotide is approved for the treatment of sinusoidal obstruction syndrome after allogeneic stem cell transplantation. The exact mode of action of defibrotide is unclear and human in vivo data are scarce. In this randomized, double blind, crossover trial we included 20 healthy volunteers. Four wer...
Autores principales: | Schoergenhofer, Christian, Buchtele, Nina, Gelbenegger, Georg, Derhaschnig, Ulla, Firbas, Christa, Kovacevic, Katarina D., Schwameis, Michael, Wohlfarth, Philipp, Rabitsch, Werner, Jilma, Bernd |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668569/ https://www.ncbi.nlm.nih.gov/pubmed/31366975 http://dx.doi.org/10.1038/s41598-019-47630-6 |
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