Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force

We investigated the mechanical unfolding of single spectrin molecules over a broad range of loading rates and thus unfolding forces by combining magnetic tweezers with atomic force microscopy. We find that the mean unfolding force increases logarithmically with loading rate at low loading rates, but...

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Detalles Bibliográficos
Autores principales: Renn, J. P., Bhattacharyya, S., Bai, H., He, C., Li, H., Oberhauser, A. F., Marko, J. F., Makarov, D. E., Matouschek, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668576/
https://www.ncbi.nlm.nih.gov/pubmed/31366931
http://dx.doi.org/10.1038/s41598-019-46525-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668576/
https://www.ncbi.nlm.nih.gov/pubmed/31366931
http://dx.doi.org/10.1038/s41598-019-46525-w

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