Cargando…
Mechanical unfolding of spectrin reveals a super-exponential dependence of unfolding rate on force
We investigated the mechanical unfolding of single spectrin molecules over a broad range of loading rates and thus unfolding forces by combining magnetic tweezers with atomic force microscopy. We find that the mean unfolding force increases logarithmically with loading rate at low loading rates, but...
Autores principales: | Renn, J. P., Bhattacharyya, S., Bai, H., He, C., Li, H., Oberhauser, A. F., Marko, J. F., Makarov, D. E., Matouschek, A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668576/ https://www.ncbi.nlm.nih.gov/pubmed/31366931 http://dx.doi.org/10.1038/s41598-019-46525-w |
Ejemplares similares
-
Protein Unfolding: Denaturant vs. Force
por: Kelly, Colleen, et al.
Publicado: (2021) -
Unfolding the Unfolded Protein Response: Unique Insights into Brain Ischemia
por: Sanderson, Thomas H., et al.
Publicado: (2015) -
Unfolding algorithms and tests using RooUnfold
por: Adye, Tim
Publicado: (2011) -
Unfolded Protein Responses With or Without Unfolded Proteins?
por: Snapp, Erik L.
Publicado: (2012) -
Protein Unfolding—Thermodynamic Perspectives and Unfolding Models
por: Seelig, Joachim, et al.
Publicado: (2023)