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Conserved Herpesvirus Protein Kinases Target SAMHD1 to Facilitate Virus Replication

To ensure a successful infection, herpesviruses have developed elegant strategies to counterbalance the host anti-viral responses. Sterile alpha motif and HD domain 1 (SAMHD1) was recently identified as an intrinsic restriction factor for a variety of viruses. Aside from HIV-2 and the related simian...

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Detalles Bibliográficos
Autores principales: Zhang, Kun, Lv, Dong-Wen, Li, Renfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668718/
https://www.ncbi.nlm.nih.gov/pubmed/31291580
http://dx.doi.org/10.1016/j.celrep.2019.04.020