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Assessing key decisions for transcriptomic data integration in biochemical networks
To gain insights into complex biological processes, genome-scale data (e.g., RNA-Seq) are often overlaid on biochemical networks. However, many networks do not have a one-to-one relationship between genes and network edges, due to the existence of isozymes and protein complexes. Therefore, decisions...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668847/ https://www.ncbi.nlm.nih.gov/pubmed/31323017 http://dx.doi.org/10.1371/journal.pcbi.1007185 |