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Generation of IL-3–Secreting CD4(+) T Cells by Microbial Challenge at Skin and Mucosal Barriers

During Ag priming, naive CD4(+) T cells differentiate into subsets with distinct patterns of cytokine expression that dictate to a major extent their functional roles in immune responses. We identified a subset of CD4(+) T cells defined by secretion of IL-3 that was induced by Ag stimulation under c...

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Detalles Bibliográficos
Autores principales: Kunnath-Velayudhan, Shajo, Goldberg, Michael F., Saini, Neeraj K., Ng, Tony W., Arora, Pooja, Johndrow, Christopher T., Saavedra-Avila, Noemi Alejandra, Johnson, Alison J., Xu, Jiayong, Kim, John, Khajoueinejad, Nazanin, Petro, Christopher D., Herold, Betsy C., Lauvau, Gregoire, Chan, John, Jacobs, William R., Porcelli, Steven A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668923/
https://www.ncbi.nlm.nih.gov/pubmed/31356170
http://dx.doi.org/10.4049/immunohorizons.1900028