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Effect of inoculum density on human‐induced pluripotent stem cell expansion in 3D bioreactors

OBJECTIVE: For optimized expansion of human‐induced pluripotent stem cells (hiPSCs) with regards to clinical applications, we investigated the influence of the inoculum density on the expansion procedure in 3D hollow‐fibre bioreactors. MATERIALS AND METHODS: Analytical‐scale bioreactors with a cell...

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Detalles Bibliográficos
Autores principales: Greuel, Selina, Hanci, Güngör, Böhme, Mike, Miki, Toshio, Schubert, Frank, Sittinger, Michael, Mandenius, Carl‐Fredrik, Zeilinger, Katrin, Freyer, Nora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668975/
https://www.ncbi.nlm.nih.gov/pubmed/31069891
http://dx.doi.org/10.1111/cpr.12604