Golgi phosphoprotein 3 sensitizes the tumour suppression effect of gefitinib on gliomas

OBJECTIVES: We previously reported that Golgi phosphoprotein 3 (GOLPH3) promotes glioma progression by inhibiting EGFR endocytosis and degradation, leading to EGFR accumulation and PI3K‐AKT pathway over‐activation. In the current study, we examine whether GOLPH3 affects the response of glioma cells...

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Detalles Bibliográficos
Autores principales: Wang, Xu, Wang, Zhaohao, Zhang, Yu, Wang, Yan, Zhang, Hao, Xie, Shao, Xie, Peng, Yu, Rutong, Zhou, Xiuping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669003/
https://www.ncbi.nlm.nih.gov/pubmed/31094020
http://dx.doi.org/10.1111/cpr.12636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669003/
https://www.ncbi.nlm.nih.gov/pubmed/31094020
http://dx.doi.org/10.1111/cpr.12636

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