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Covalent chemistry on nanostructured substrates enables noninvasive quantification of gene rearrangements in circulating tumor cells
Well-preserved mRNA in circulating tumor cells (CTCs) offers an ideal material for conducting molecular profiling of tumors, thereby providing a noninvasive diagnostic solution for guiding treatment intervention and monitoring disease progression. However, it is technically challenging to purify CTC...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669017/ https://www.ncbi.nlm.nih.gov/pubmed/31392269 http://dx.doi.org/10.1126/sciadv.aav9186 |