Sugar Modification Enhances Cytotoxic Activity of PAMAM-Doxorubicin Conjugate in Glucose-Deprived MCF-7 Cells – Possible Role of GLUT1 Transporter

PURPOSE: In order to overcome the obstacles and side effects of classical chemotherapy, numerous studies have been performed to develop the treatment based on targeted transport of active compounds directly to the site of action. Since tumor cells are featured with intensified glucose metabolism, we...

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Detalles Bibliográficos
Autores principales: Sztandera, Krzysztof, Działak, Paula, Marcinkowska, Monika, Stańczyk, Maciej, Gorzkiewicz, Michał, Janaszewska, Anna, Klajnert-Maculewicz, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669199/
https://www.ncbi.nlm.nih.gov/pubmed/31367876
http://dx.doi.org/10.1007/s11095-019-2673-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669199/
https://www.ncbi.nlm.nih.gov/pubmed/31367876
http://dx.doi.org/10.1007/s11095-019-2673-9

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