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Human biodistribution and radiation dosimetry of the 5-HT(2A) receptor agonist Cimbi-36 labeled with carbon-11 in two positions

BACKGROUND: Cimbi-36 can be (11)C-labeled to form an agonist radioligand used for positron emission tomography (PET) imaging of the 5-HT(2A) receptor in the brain. In its non-labeled form (25B-NBOMe), it is used as a recreational drug that can lead to severe adverse effects, in some cases, with fata...

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Detalles Bibliográficos
Autores principales: Johansen, Annette, Holm, Søren, Dall, Bente, Keller, Sune, Kristensen, Jesper L., Knudsen, Gitte M., Hansen, Hanne D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669221/
https://www.ncbi.nlm.nih.gov/pubmed/31367837
http://dx.doi.org/10.1186/s13550-019-0527-4