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Loxapine for Treatment of Patients With Refractory, Chemotherapy-Induced Neuropathic Pain: A Prematurely Terminated Pilot Study Showing Efficacy But Limited Tolerability

Neuropathic pain is a debilitating and commonly treatment-refractory condition requiring novel therapeutic options. Accumulating preclinical studies indicate that the potassium channel Slack (K(Na)1.1) contributes to the processing of neuropathic pain, and that Slack activators, when injected into m...

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Detalles Bibliográficos
Autores principales: Schmiedl, Sven, Peters, David, Schmalz, Oliver, Mielke, Anke, Rossmanith, Tanja, Diop, Shirin, Piefke, Martina, Thürmann, Petra, Schmidtko, Achim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669235/
https://www.ncbi.nlm.nih.gov/pubmed/31402867
http://dx.doi.org/10.3389/fphar.2019.00838