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Loxapine for Treatment of Patients With Refractory, Chemotherapy-Induced Neuropathic Pain: A Prematurely Terminated Pilot Study Showing Efficacy But Limited Tolerability
Neuropathic pain is a debilitating and commonly treatment-refractory condition requiring novel therapeutic options. Accumulating preclinical studies indicate that the potassium channel Slack (K(Na)1.1) contributes to the processing of neuropathic pain, and that Slack activators, when injected into m...
Autores principales: | Schmiedl, Sven, Peters, David, Schmalz, Oliver, Mielke, Anke, Rossmanith, Tanja, Diop, Shirin, Piefke, Martina, Thürmann, Petra, Schmidtko, Achim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669235/ https://www.ncbi.nlm.nih.gov/pubmed/31402867 http://dx.doi.org/10.3389/fphar.2019.00838 |
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