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Hippocampal neurons in direct contact with astrocytes exposed to amyloid β(25-35) exhibit reduced excitatory synaptic transmission

Amyloid β protein (Aβ) is closely related to the progression of Alzheimer's disease because senile plaques consisting of Aβ cause synaptic depression and synaptic abnormalities. In the central nervous system, astrocytes are a major glial cell type that contribute to the modulation of synaptic t...

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Detalles Bibliográficos
Autores principales: Oyabu, Kohei, Kiyota, Hiroki, Kubota, Kaori, Watanabe, Takuya, Katsurabayashi, Shutaro, Iwasaki, Katsunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669318/
https://www.ncbi.nlm.nih.gov/pubmed/31388597
http://dx.doi.org/10.1016/j.ibror.2019.07.1719