Cargando…
Hippocampal neurons in direct contact with astrocytes exposed to amyloid β(25-35) exhibit reduced excitatory synaptic transmission
Amyloid β protein (Aβ) is closely related to the progression of Alzheimer's disease because senile plaques consisting of Aβ cause synaptic depression and synaptic abnormalities. In the central nervous system, astrocytes are a major glial cell type that contribute to the modulation of synaptic t...
Autores principales: | Oyabu, Kohei, Kiyota, Hiroki, Kubota, Kaori, Watanabe, Takuya, Katsurabayashi, Shutaro, Iwasaki, Katsunori |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669318/ https://www.ncbi.nlm.nih.gov/pubmed/31388597 http://dx.doi.org/10.1016/j.ibror.2019.07.1719 |
Ejemplares similares
-
Valproic acid-exposed astrocytes impair inhibitory synapse formation and function
por: Takeda, Kotomi, et al.
Publicado: (2021) -
Overexpression of Swedish mutant APP in aged astrocytes attenuates excitatory synaptic transmission
por: Katsurabayashi, Shutaro, et al.
Publicado: (2016) -
Establishment of autaptic culture with human-induced pluripotent stem cell-derived astrocytes
por: Uchino, Kouya, et al.
Publicado: (2022) -
Ninjinyoeito Prevents Onset of Depression-Like Behavior and Reduces Hippocampal iNOS Expression in Senescence-Accelerated Mouse Prone 8 Mice
por: Taniguchi, Chise, et al.
Publicado: (2023) -
Long-Term Culture of Astrocytes Attenuates the Readily Releasable Pool of Synaptic Vesicles
por: Kawano, Hiroyuki, et al.
Publicado: (2012)