Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39

OBJECTIVES: We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these genetic loci for stratifying drug response. M...

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Detalles Bibliográficos
Autores principales: Spiliopoulou, Athina, Colombo, Marco, Plant, Darren, Nair, Nisha, Cui, Jing, Coenen, Marieke JH, Ikari, Katsunori, Yamanaka, Hisashi, Saevarsdottir, Saedis, Padyukov, Leonid, Bridges Jr., S Louis, Kimberly, Robert P, Okada, Yukinori, van Riel, Piet L CM, Wolbink, Gertjan, van der Horst-Bruinsma, Irene E, de Vries, Niek, Tak, Paul P, Ohmura, Koichiro, Canhão, Helena, Guchelaar, Henk-Jan, Huizinga, Tom WJ, Criswell, Lindsey A, Raychaudhuri, Soumya, Weinblatt, Michael E, Wilson, Anthony G, Mariette, Xavier, Isaacs, John D, Morgan, Ann W, Pitzalis, Costantino, Barton, Anne, McKeigue, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669378/
https://www.ncbi.nlm.nih.gov/pubmed/31036624
http://dx.doi.org/10.1136/annrheumdis-2018-214877