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Association of response to TNF inhibitors in rheumatoid arthritis with quantitative trait loci for CD40 and CD39
OBJECTIVES: We sought to investigate whether genetic effects on response to TNF inhibitors (TNFi) in rheumatoid arthritis (RA) could be localised by considering known genetic susceptibility loci for relevant traits and to evaluate the usefulness of these genetic loci for stratifying drug response. M...
Autores principales: | Spiliopoulou, Athina, Colombo, Marco, Plant, Darren, Nair, Nisha, Cui, Jing, Coenen, Marieke JH, Ikari, Katsunori, Yamanaka, Hisashi, Saevarsdottir, Saedis, Padyukov, Leonid, Bridges Jr., S Louis, Kimberly, Robert P, Okada, Yukinori, van Riel, Piet L CM, Wolbink, Gertjan, van der Horst-Bruinsma, Irene E, de Vries, Niek, Tak, Paul P, Ohmura, Koichiro, Canhão, Helena, Guchelaar, Henk-Jan, Huizinga, Tom WJ, Criswell, Lindsey A, Raychaudhuri, Soumya, Weinblatt, Michael E, Wilson, Anthony G, Mariette, Xavier, Isaacs, John D, Morgan, Ann W, Pitzalis, Costantino, Barton, Anne, McKeigue, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669378/ https://www.ncbi.nlm.nih.gov/pubmed/31036624 http://dx.doi.org/10.1136/annrheumdis-2018-214877 |
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