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Coxsackievirus-B4 Infection of Human Primary Pancreatic Ductal Cell Cultures Results in Impairment of Differentiation into Insulin-Producing Cells

Coxsackievirus-B4 (CV-B4) E2 can persist in the pancreatic ductal-like cells (Panc-1 cell line), which results in an impaired differentiation of these cells into islet-like cell aggregates (ICA). In this study, primary pancreatic ductal cells obtained as a by-product of islet isolation from the panc...

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Detalles Bibliográficos
Autores principales: Bertin, Antoine, Sane, Famara, Gmyr, Valery, Lobert, Delphine, Dechaumes, Arthur, Kerr-Conte, Julie, Pattou, François, Hober, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669621/
https://www.ncbi.nlm.nih.gov/pubmed/31269669
http://dx.doi.org/10.3390/v11070597