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In Vitro and In Vivo Antimalarial Activity of LZ1, a Peptide Derived from Snake Cathelicidin

Antimalarial drug resistance is an enormous global threat. Recently, antimicrobial peptides (AMPs) are emerging as a new source of antimalarials. In this study, an AMP LZ1 derived from snake cathelicidin was identified with antimalarial activity. In the in vitro antiplasmodial assay, LZ1 showed stro...

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Detalles Bibliográficos
Autores principales: Fang, Yaqun, He, Xiaoqin, Zhang, Pengcheng, Shen, Chuanbin, Mwangi, James, Xu, Cheng, Mo, Guoxiang, Lai, Ren, Zhang, Zhiye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669622/
https://www.ncbi.nlm.nih.gov/pubmed/31262018
http://dx.doi.org/10.3390/toxins11070379