Reverse Genetics of RNA Viruses: ISA-Based Approach to Control Viral Population Diversity without Modifying Virus Phenotype

Reverse genetic systems are essential for the study of RNA viruses. Infectious clones remain the most widely used systems to manipulate viral genomes. Recently, a new PCR-based method called ISA (infectious subgenomic amplicons) has been developed. This approach has resulted in greater genetic diver...

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Detalles Bibliográficos
Autores principales: Driouich, Jean-Sélim, Moureau, Gregory, de Lamballerie, Xavier, Nougairède, Antoine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669666/
https://www.ncbi.nlm.nih.gov/pubmed/31330809
http://dx.doi.org/10.3390/v11070666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669666/
https://www.ncbi.nlm.nih.gov/pubmed/31330809
http://dx.doi.org/10.3390/v11070666

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