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LC-HRMS Screening and Identification of Novel Peptide Markers of Ricin Based on Multiple Protease Digestion Strategies

Both ricin and R. communis agglutinin (RCA120), belonging to the type II ribosome-inactivating proteins (RIPs-Ⅱ), are derived from the seeds of the castor bean plant. They share very similar amino acid sequences, but ricin is much more toxic than RCA120. It is urgently necessary to distinguish ricin...

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Detalles Bibliográficos
Autores principales: Liang, Long-Hui, Liu, Chang-Cai, Chen, Bo, Yan, Long, Yu, Hui-Lan, Yang, Yang, Wu, Ji-Na, Li, Xiao-Sen, Liu, Shi-Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669667/
https://www.ncbi.nlm.nih.gov/pubmed/31284465
http://dx.doi.org/10.3390/toxins11070393