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ADAR1: “Editor-in-Chief” of Cytoplasmic Innate Immunity

Specialized receptors that recognize molecular patterns such as double stranded RNA duplexes—indicative of viral replication—are potent triggers of the innate immune system. Although their activation is beneficial during viral infection, RNA transcribed from endogenous mobile genetic elements may al...

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Detalles Bibliográficos
Autores principales: Lamers, Mart M., van den Hoogen, Bernadette G., Haagmans, Bart L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6669771/
https://www.ncbi.nlm.nih.gov/pubmed/31404141
http://dx.doi.org/10.3389/fimmu.2019.01763