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Solid pseudopapillary neoplasms of the pancreas are dependent on the Wnt pathway

Solid pseudopapillary neoplasms (SPNs) are rare and relatively indolent tumors of the pancreas. While primary SPNs can be surgically resected, there are currently no therapies available for patients with advanced stage disease. Given that these tumors frequently carry CTNNB1 hotspot (recurrently mut...

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Detalles Bibliográficos
Autores principales: Selenica, Pier, Raj, Nitya, Kumar, Rahul, Brown, David N., Arqués, Oriol, Reidy, Diane, Klimstra, David, Snuderl, Matija, Serrano, Jonathan, Palmer, Héctor G., Weigelt, Britta, Reis‐Filho, Jorge S., Scaltriti, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670010/
https://www.ncbi.nlm.nih.gov/pubmed/30972907
http://dx.doi.org/10.1002/1878-0261.12490