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Solid pseudopapillary neoplasms of the pancreas are dependent on the Wnt pathway
Solid pseudopapillary neoplasms (SPNs) are rare and relatively indolent tumors of the pancreas. While primary SPNs can be surgically resected, there are currently no therapies available for patients with advanced stage disease. Given that these tumors frequently carry CTNNB1 hotspot (recurrently mut...
Autores principales: | Selenica, Pier, Raj, Nitya, Kumar, Rahul, Brown, David N., Arqués, Oriol, Reidy, Diane, Klimstra, David, Snuderl, Matija, Serrano, Jonathan, Palmer, Héctor G., Weigelt, Britta, Reis‐Filho, Jorge S., Scaltriti, Maurizio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670010/ https://www.ncbi.nlm.nih.gov/pubmed/30972907 http://dx.doi.org/10.1002/1878-0261.12490 |
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