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Detection of mutational patterns in cell‐free DNA of colorectal cancer by custom amplicon sequencing

Monitoring the mutational patterns of solid tumors during cancer therapy is a major challenge in oncology. Analysis of mutations in cell‐free (cf) DNA offers a noninvasive approach to detect mutations that may be prognostic for disease survival or predictive for primary or secondary drug resistance....

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Detalles Bibliográficos
Autores principales: Herrmann, Simon, Zhan, Tianzuo, Betge, Johannes, Rauscher, Benedikt, Belle, Sebastian, Gutting, Tobias, Schulte, Nadine, Jesenofsky, Ralf, Härtel, Nicolai, Gaiser, Timo, Hofheinz, Ralf‐Dieter, Ebert, Matthias P., Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670011/
https://www.ncbi.nlm.nih.gov/pubmed/31254442
http://dx.doi.org/10.1002/1878-0261.12539