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Xenograft and organoid model systems in cancer research

Patient‐derived tumour xenografts and tumour organoids have become important preclinical model systems for cancer research. Both models maintain key features from their parental tumours, such as genetic and phenotypic heterogeneity, which allows them to be used for a wide spectrum of applications. I...

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Detalles Bibliográficos
Autores principales: Bleijs, Margit, van de Wetering, Marc, Clevers, Hans, Drost, Jarno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670015/
https://www.ncbi.nlm.nih.gov/pubmed/31282586
http://dx.doi.org/10.15252/embj.2019101654