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Xenograft and organoid model systems in cancer research
Patient‐derived tumour xenografts and tumour organoids have become important preclinical model systems for cancer research. Both models maintain key features from their parental tumours, such as genetic and phenotypic heterogeneity, which allows them to be used for a wide spectrum of applications. I...
Autores principales: | Bleijs, Margit, van de Wetering, Marc, Clevers, Hans, Drost, Jarno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670015/ https://www.ncbi.nlm.nih.gov/pubmed/31282586 http://dx.doi.org/10.15252/embj.2019101654 |
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