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Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model

BACKGROUND: Doxorubicin is currently the most effective chemotherapeutic drug used to treat breast cancer. It has, however, been shown that doxorubicin can induce drug resistance resulting in poor patient prognosis and survival. Studies reported that the interaction between signalling pathways can p...

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Detalles Bibliográficos
Autores principales: Christowitz, Claudia, Davis, Tanja, Isaacs, Ashwin, van Niekerk, Gustav, Hattingh, Suzel, Engelbrecht, Anna-Mart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670209/
https://www.ncbi.nlm.nih.gov/pubmed/31370818
http://dx.doi.org/10.1186/s12885-019-5939-z