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Mechanisms of doxorubicin-induced drug resistance and drug resistant tumour growth in a murine breast tumour model
BACKGROUND: Doxorubicin is currently the most effective chemotherapeutic drug used to treat breast cancer. It has, however, been shown that doxorubicin can induce drug resistance resulting in poor patient prognosis and survival. Studies reported that the interaction between signalling pathways can p...
Autores principales: | Christowitz, Claudia, Davis, Tanja, Isaacs, Ashwin, van Niekerk, Gustav, Hattingh, Suzel, Engelbrecht, Anna-Mart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670209/ https://www.ncbi.nlm.nih.gov/pubmed/31370818 http://dx.doi.org/10.1186/s12885-019-5939-z |
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