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The effect of dicarbonyl stress on the development of kidney dysfunction in metabolic syndrome – a transcriptomic and proteomic approach

BACKGROUND AND AIMS: Dicarbonyl stress plays an important role in the pathogenesis of microvascular complications that precede the formation of advanced glycation end products, and contributes to the development of renal dysfunction. In renal cells, toxic metabolites like methylglyoxal lead to mitoc...

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Detalles Bibliográficos
Autores principales: Markova, Irena, Hüttl, Martina, Oliyarnyk, Olena, Kacerova, Tereza, Haluzik, Martin, Kacer, Petr, Seda, Ondrej, Malinska, Hana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670216/
https://www.ncbi.nlm.nih.gov/pubmed/31388341
http://dx.doi.org/10.1186/s12986-019-0376-1