Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells

BACKGROUND: Glioblastoma multiforme (GBM) is the most severe type of primary brain tumor with a high mortality rate. Although extensive treatments for GBM, including resection, irradiation, chemotherapy and immunotherapy, have been tried, the prognosis is still poor. Temozolomide (TMZ), an alkylatin...

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Detalles Bibliográficos
Autores principales: Chen, Jui-Chieh, Lee, I-Neng, Huang, Cheng, Wu, Yu-Ping, Chung, Chiu-Yen, Lee, Ming-Hsueh, Lin, Martin Hsiu-Chu, Yang, Jen-Tsung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670223/
https://www.ncbi.nlm.nih.gov/pubmed/31370819
http://dx.doi.org/10.1186/s12885-019-5843-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670223/
https://www.ncbi.nlm.nih.gov/pubmed/31370819
http://dx.doi.org/10.1186/s12885-019-5843-6

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