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Valproic acid-induced amphiregulin secretion confers resistance to temozolomide treatment in human glioma cells
BACKGROUND: Glioblastoma multiforme (GBM) is the most severe type of primary brain tumor with a high mortality rate. Although extensive treatments for GBM, including resection, irradiation, chemotherapy and immunotherapy, have been tried, the prognosis is still poor. Temozolomide (TMZ), an alkylatin...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670223/ https://www.ncbi.nlm.nih.gov/pubmed/31370819 http://dx.doi.org/10.1186/s12885-019-5843-6 |