Outlook for coeliac disease patients: towards bread wheat with hypoimmunogenic gluten by gene editing of α- and γ-gliadin gene families

BACKGROUND: Wheat grains contain gluten proteins, which harbour immunogenic epitopes that trigger Coeliac disease in 1–2% of the human population. Wheat varieties or accessions containing only safe gluten have not been identified and conventional breeding alone struggles to achieve such a goal, as t...

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Detalles Bibliográficos
Autores principales: Jouanin, Aurélie, Schaart, Jan G., Boyd, Lesley A., Cockram, James, Leigh, Fiona J., Bates, Ruth, Wallington, Emma J., Visser, Richard G. F., Smulders, Marinus J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670228/
https://www.ncbi.nlm.nih.gov/pubmed/31370789
http://dx.doi.org/10.1186/s12870-019-1889-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670228/
https://www.ncbi.nlm.nih.gov/pubmed/31370789
http://dx.doi.org/10.1186/s12870-019-1889-5

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