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Claudin-low-like mouse mammary tumors show distinct transcriptomic patterns uncoupled from genomic drivers

BACKGROUND: Claudin-low breast cancer is a molecular subtype associated with poor prognosis and without targeted treatment options. The claudin-low subtype is defined by certain biological characteristics, some of which may be clinically actionable, such as high immunogenicity. In mice, the medroxyp...

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Detalles Bibliográficos
Autores principales: Fougner, Christian, Bergholtz, Helga, Kuiper, Raoul, Norum, Jens Henrik, Sørlie, Therese
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670237/
https://www.ncbi.nlm.nih.gov/pubmed/31366361
http://dx.doi.org/10.1186/s13058-019-1170-8