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Selective TACE with irinotecan-loaded 40 μm microspheres and FOLFIRI for colorectal liver metastases: phase I dose escalation pharmacokinetic study

BACKGROUND: Efficacy of treatments for colorectal liver metastases after failure of first-line chemotherapy is limited. The aim of this study was to prospectively evaluate the feasibility, tolerability, and pharmacokinetics of selective transarterial chemoembolization (TACE) with irinotecan-loaded 4...

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Detalles Bibliográficos
Autores principales: Tanaka, Toshihiro, Sato, Takeshi, Nishiofuku, Hideyuki, Masada, Tetsuya, Tatsumoto, Shota, Marugami, Nagaaki, Otsuji, Toshio, Kanno, Masatoshi, Koyama, Fumikazu, Sho, Masayuki, Kichikawa, Kimihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670239/
https://www.ncbi.nlm.nih.gov/pubmed/31370815
http://dx.doi.org/10.1186/s12885-019-5862-3