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A Dual Inhibitor of Cdc7/Cdk9 Potently Suppresses T Cell Activation
T cell activation is mediated by signaling pathways originating from the T cell receptor (TCR). Propagation of signals downstream of the TCR involves a cascade of numerous kinases, some of which have yet to be identified. Through a screening strategy that we have previously introduced, PHA-767491, a...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670834/ https://www.ncbi.nlm.nih.gov/pubmed/31402912 http://dx.doi.org/10.3389/fimmu.2019.01718 |