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Liver Proliferation Is an Essential Driver of Fibrosis in Mouse Models of Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) involves development of hepatic steatosis, fibrosis, and steatohepatitis. Because hepatic steatosis appears first in NAFLD animal models, the current therapy development focuses on inhibition of hepatic steatosis, suggesting that further steps of NAFLD will b...

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Detalles Bibliográficos
Autores principales: Cast, Ashley, Kumbaji, Meenasri, D'Souza, Amber, Rodriguez, Katherine, Gupta, Anita, Karns, Rebekah, Timchenko, Lubov, Timchenko, Nikolai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671863/
https://www.ncbi.nlm.nih.gov/pubmed/31388625
http://dx.doi.org/10.1002/hep4.1381