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Polymyxins and Their Potential Next Generation as Therapeutic Antibiotics
The discovery of polymyxins, highly basic lipodecapeptides, was published independently by three laboratories in 1947. Their clinical use, however, was abandoned in the sixties because of nephrotoxicity and because better-tolerated drugs belonging to other antibiotic classes were discovered. Now pol...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671869/ https://www.ncbi.nlm.nih.gov/pubmed/31404242 http://dx.doi.org/10.3389/fmicb.2019.01689 |