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NAD-Biosynthetic and Consuming Enzymes as Central Players of Metabolic Regulation of Innate and Adaptive Immune Responses in Cancer

Cancer cells, particularly in solid tumors, are surrounded by non-neoplastic elements, including endothelial and stromal cells, as well as cells of immune origin, which can support tumor growth by providing the right conditions. On the other hand, local hypoxia, and lack of nutrients induce tumor ce...

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Detalles Bibliográficos
Autores principales: Audrito, Valentina, Managò, Antonella, Gaudino, Federica, Sorci, Leonardo, Messana, Vincenzo Gianluca, Raffaelli, Nadia, Deaglio, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671870/
https://www.ncbi.nlm.nih.gov/pubmed/31402913
http://dx.doi.org/10.3389/fimmu.2019.01720