Human thioredoxin, a damage-associated molecular pattern and Malassezia-crossreactive autoallergen, modulates immune responses via the C-type lectin receptors Dectin-1 and Dectin-2

Human thioredoxin (hTrx), which can be secreted from cells upon stress, functions in allergic skin inflammation as a T cell antigen due to homology and cross-reactivity with the fungal allergen Mala s13 of the skin-colonizing yeast Malassezia sympodialis. Recent studies have shown that cell wall pol...

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Detalles Bibliográficos
Autores principales: Roesner, L. M., Ernst, M., Chen, W., Begemann, G., Kienlin, P., Raulf, M. K., Lepenies, B., Werfel, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671947/
https://www.ncbi.nlm.nih.gov/pubmed/31371767
http://dx.doi.org/10.1038/s41598-019-47769-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671947/
https://www.ncbi.nlm.nih.gov/pubmed/31371767
http://dx.doi.org/10.1038/s41598-019-47769-2

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