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Regioisomer-independent quantification of fatty acid oxidation products by HPLC-ESI-MS/MS analysis of sodium adducts
Despite growing acknowledgement of the role of oxidized fatty acids (oxFA) as cellular signaling molecules and in the pathogenesis of disease, developing methods to measure these species in biological samples has proven challenging. Here we describe a novel method utilizing HPLC-ESI-MS/MS to identif...
Autores principales: | Ahern, Katelyn W., Serbulea, Vlad, Wingrove, Catherine L., Palas, Zachary T., Leitinger, Norbert, Harris, Thurl E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671977/ https://www.ncbi.nlm.nih.gov/pubmed/31371760 http://dx.doi.org/10.1038/s41598-019-47693-5 |
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