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β-amyloid pathology and hippocampal atrophy are independently associated with memory function in cognitively healthy elderly

The independent effects of different brain pathologies on age-dependent cognitive decline are unclear. We examined this in 300 cognitively unimpaired elderly individuals from the BioFINDER study. Using cognition as outcome we studied the effects of cerebrospinal fluid biomarkers for amyloid-β (Aβ42/...

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Detalles Bibliográficos
Autores principales: Svenningsson, Anna L., Stomrud, Erik, Insel, Philip S., Mattsson, Niklas, Palmqvist, Sebastian, Hansson, Oskar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671981/
https://www.ncbi.nlm.nih.gov/pubmed/31371787
http://dx.doi.org/10.1038/s41598-019-47638-y