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Spatial Regulation of Mitochondrial Heterogeneity by Stromal Confinement in Micropatterned Tumor Models

Heterogeneity of mitochondrial activities in cancer cells exists across different disease stages and even in the same patient, with increased mitochondrial activities associated with invasive cancer phenotypes and circulating tumor cells. Here, we use a micropatterned tumor-stromal assay (μTSA) comp...

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Detalles Bibliográficos
Autores principales: Begum, Hydari Masuma, Ta, Hoang P., Zhou, Hao, Ando, Yuta, Kang, Diane, Nemes, Kristen, Mariano, Chelsea F., Hao, Jia, Yu, Min, Shen, Keyue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6671984/
https://www.ncbi.nlm.nih.gov/pubmed/31371796
http://dx.doi.org/10.1038/s41598-019-47593-8