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The autism- and schizophrenia-associated protein CYFIP1 regulates bilateral brain connectivity and behaviour

Copy-number variants of the CYFIP1 gene in humans have been linked to autism spectrum disorders (ASD) and schizophrenia (SCZ), two neuropsychiatric disorders characterized by defects in brain connectivity. Here, we show that CYFIP1 plays an important role in brain functional connectivity and callosa...

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Detalles Bibliográficos
Autores principales: Domínguez-Iturza, Nuria, Lo, Adrian C., Shah, Disha, Armendáriz, Marcelo, Vannelli, Anna, Mercaldo, Valentina, Trusel, Massimo, Li, Ka Wan, Gastaldo, Denise, Santos, Ana Rita, Callaerts-Vegh, Zsuzsanna, D’Hooge, Rudi, Mameli, Manuel, Van der Linden, Annemie, Smit, August B., Achsel, Tilmann, Bagni, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672001/
https://www.ncbi.nlm.nih.gov/pubmed/31371726
http://dx.doi.org/10.1038/s41467-019-11203-y