Rivaroxaban, a specific FXa inhibitor, improved endothelium-dependent relaxation of aortic segments in diabetic mice

Activated factor X (FXa) plays a central role in the coagulation cascade, while it also mediates vascular function through activation of protease-activated receptors (PARs). Here, we examined whether inhibition of FXa by rivaroxaban, a direct FXa inhibitor, attenuates endothelial dysfunction in stre...

Descripción completa

Detalles Bibliográficos
Autores principales: Pham, Phuong Tran, Fukuda, Daiju, Yagi, Shusuke, Kusunose, Kenya, Yamada, Hirotsugu, Soeki, Takeshi, Shimabukuro, Michio, Sata, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672013/
https://www.ncbi.nlm.nih.gov/pubmed/31371788
http://dx.doi.org/10.1038/s41598-019-47474-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672013/
https://www.ncbi.nlm.nih.gov/pubmed/31371788
http://dx.doi.org/10.1038/s41598-019-47474-0

Ejemplares similares