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Promoter-proximal pausing of RNA polymerase II: a nexus of gene regulation

Precise spatio–temporal control of gene activity is essential for organismal development, growth, and survival in a changing environment. Decisive steps in gene regulation involve the pausing of RNA polymerase II (Pol II) in early elongation, and the controlled release of paused polymerase into prod...

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Detalles Bibliográficos
Autores principales: Core, Leighton, Adelman, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6672056/
https://www.ncbi.nlm.nih.gov/pubmed/31123063
http://dx.doi.org/10.1101/gad.325142.119