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Hedgehog Interacting Protein (Hhip) Regulates Insulin Secretion in Mice Fed High Fat Diets

Hedgehog interacting protein (Hhip) is essential for islet formation and beta-cell proliferation during pancreatic development; abnormally elevated Hhip expression has been linked to human pancreatitis. Here, we investigate the role of Hhip in modulating insulin secretion in adult Hhip mice (Hhip +/...

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Detalles Bibliográficos
Autores principales: Nchienzia, Henry, Liao, Min-Chun, Zhao, Xin-Ping, Chang, Shiao-Ying, Lo, Chao-Sheng, Chenier, Isabelle, Ingelfinger, Julie R., Chan, John S. D., Zhang, Shao-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673691/
https://www.ncbi.nlm.nih.gov/pubmed/31371780
http://dx.doi.org/10.1038/s41598-019-47633-3