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Capture of a functionally active methyl-CpG binding domain by an arthropod retrotransposon family

The repressive capacity of cytosine DNA methylation is mediated by recruitment of silencing complexes by methyl-CpG binding domain (MBD) proteins. Despite MBD proteins being associated with silencing, we discovered that a family of arthropod Copia retrotransposons have incorporated a host-derived MB...

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Detalles Bibliográficos
Autores principales: de Mendoza, Alex, Pflueger, Jahnvi, Lister, Ryan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673714/
https://www.ncbi.nlm.nih.gov/pubmed/31239280
http://dx.doi.org/10.1101/gr.243774.118