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BiosyntheticSPAdes: reconstructing biosynthetic gene clusters from assembly graphs

Predicting biosynthetic gene clusters (BGCs) is critically important for discovery of antibiotics and other natural products. While BGC prediction from complete genomes is a well-studied problem, predicting BGCs in fragmented genomic assemblies remains challenging. The existing BGC prediction tools...

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Detalles Bibliográficos
Autores principales: Meleshko, Dmitry, Mohimani, Hosein, Tracanna, Vittorio, Hajirasouliha, Iman, Medema, Marnix H., Korobeynikov, Anton, Pevzner, Pavel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673720/
https://www.ncbi.nlm.nih.gov/pubmed/31160374
http://dx.doi.org/10.1101/gr.243477.118