Efficient and flexible tagging of endogenous genes by homology-independent intron targeting

Genome editing tools have simplified the generation of knock-in gene fusions, yet the prevalent use of gene-specific homology-directed repair (HDR) templates still hinders scalability. Consequently, realization of large-scale gene tagging requires further development of approaches to generate knock-...

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Detalles Bibliográficos
Autores principales: Serebrenik, Yevgeniy V., Sansbury, Stephanie E., Kumar, Saranya Santhosh, Henao-Mejia, Jorge, Shalem, Ophir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673721/
https://www.ncbi.nlm.nih.gov/pubmed/31239279
http://dx.doi.org/10.1101/gr.246413.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6673721/
https://www.ncbi.nlm.nih.gov/pubmed/31239279
http://dx.doi.org/10.1101/gr.246413.118

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